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Article

Mutational landscape of AML with normal cytogenetics: biological and clinical implications.

Blood reviews - 1 Jan 2013

Martelli Maria Paola, Sportoletti Paolo, Tiacci Enrico, Martelli Massimo F, Falini Brunangelo

Abstract excerpt

Acute myeloid leukemia (AML) is a molecularly heterogeneous disease. Based on cytogenetics and FISH, AML patients are stratified into three major risk categories: favourable, intermediate and unfavourable. However, prognostic stratification and treatment decision for the intermediate risk category, that mostly comprises AML patients with normal cytogenetics (CN-AML), has been difficult due to the clinical...

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PMID: 23261068
DOI: 10.1016/j.blre.2012.11.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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