Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BDNF rs6265 differentially influences neurometabolites in the anterior cingulate of healthy and bipolar disorder subjects.

Brain imaging and behavior - 1 Jun 2023

Scotti-Muzzi Estêvão, Chile Thais, Vallada Homero, Otaduy Maria Concepción Garcia, Soeiro-de-Souza Márcio Gerhardt

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is the most abundant brain neurotrophin and plays a critical role in neuronal growth, survival and plasticity, implicated in the pathophysiology of Bipolar Disorders (BD). The single-nucleotide polymorphism in the BDNF gene (BDNF rs6265) has been associated with decreased hippocampal BDNF secretion and volume in met carriers in different populations, although the val...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Gyrus Cinguli

Share to Magnetic Resonance Imaging

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 36630045
DOI: 10.1007/s11682-023-00757-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BDNF rs6265 differentially influences neurometabolites in the anterior cingulate of healthy and bipolar disorder subjects.PMID 36630045Read ↗

Met carriers of the BDNF Val66Met polymorphism show reduced Glx/NAA in the pregenual ACC in two independent cohorts.Semantic proximity Read ↗

Met carriers of BDNF Val66Met genotype show increased N-acetylaspartate concentration in the anterior cingulate cortex.Semantic proximity Read ↗

Bcl-2 rs956572 polymorphism is associated with increased anterior cingulate cortical glutamate in euthymic bipolar I disorder.Semantic proximity Read ↗

Association between CACNA1C gene rs100737 polymorphism and glutamatergic neurometabolites in bipolar disorder.Semantic proximity Read ↗

Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar DisorderSemantic proximity Read ↗

Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system.Semantic proximity Read ↗

High blood levels of brain-derived neurotrophic factor (BDNF) mRNA in early psychosis are associated with inflammatory markers.Semantic proximity Read ↗

Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder.Semantic proximity Read ↗

ACC Glu/GABA ratio is decreased in euthymic bipolar disorder I patients: possible in vivo neurometabolite explanation for mood stabilization.Semantic proximity Read ↗

Age-modulated association between prefrontal NAA and the BDNF gene.Semantic proximity Read ↗

The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese patients with bipolar disorder and schizophrenia.Semantic proximity Read ↗

The Met allele of BDNF Val66Met polymorphism is associated with increased BDNF levels in generalized anxiety disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.