Article
High blood levels of brain-derived neurotrophic factor (BDNF) mRNA in early psychosis are associated with inflammatory markers.
Journal of psychiatric research - 1 Aug 2023
Moreno Irene, Stojanovic-Pérez Alexander, Bulduk Bengisu, Sánchez-Gistau Vanessa, Algora María José, Ortega Laura, Muntané Gerard, Vilella Elisabet, Labad Javier, Martorell Lourdes
Abstract excerpt
The brain-derived neurotrophic factor (BDNF) single nucleotide polymorphism (SNP) rs6265C > T, Val66Met, affects BDNF secretion and has been related to inflammatory processes. Both the rs6265 and BDNF protein levels have been widely investigated in neuropsychiatric disorders with conflicting results. In the present study we examined BDNF mRNA expression in blood considering the SNP rs6265 and its relationship...
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