Article
Age-modulated association between prefrontal NAA and the BDNF gene.
The international journal of neuropsychopharmacology - 1 Jul 2013
Salehi Basira, Preuss Nora, van der Veen Jan Willem, Shen Jun, Neumeister Alexander, Drevets Wayne C, Hodgkinson Colin, Goldman David, Wendland Jens R, Singleton Andrew, Gibbs Jesse R, Cookson Mark R, Hasler Gregor
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of psychiatric and neurological disorders and in the mechanisms of antidepressant pharmacotherapy. Psychiatric and neurological conditions have also been associated with reduced brain levels of N-acetyl-aspartate (NAA), which has been used as a putative marker of neural integrity. However, few studies have explored the...
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