Article
The Met allele of BDNF Val66Met polymorphism is associated with increased BDNF levels in generalized anxiety disorder.
Psychiatric genetics - 1 Oct 2015
Moreira Fernanda P, Fabião Júlia D, Bittencourt Guilherme, Wiener Carolina D, Jansen Karen, Oses Jean P, Quevedo Luciana de Ávila, Souza Luciano D M, Crispim Daisy, Portela Luiz V, Pinheiro Ricardo T, Lara Diogo R, Kaster Manuella P, da Silva Ricardo A, Ghisleni Gabriele
Abstract excerpt
BACKGROUND: Generalized anxiety disorder (GAD) is a common psychiatric disorder characterized by long-term worry, tension, nervousness, fidgeting, and symptoms of autonomic system hyperactivity. The neurobiology of this disorder is still unclear, although it has been shown consistently that the environment and the genetic profile could increase its risk. We examined whether a polymorphism in the brain-derived...
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