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Article

Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice

8 Dec 2022

Abstract excerpt

KO significantly inhibited the inflammatory response and suppressed the NLR Family Pyrin Domain Containing 3 (NLRP3) inflammasome in WAT. Altogether, we demonstrated the critical role of CCDC92 in metabolism, constituting a potential target for treating obesity and insulin resistance.

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Identifiers

PMID: 36594018
DOI: 10.1016/j.isci.2022.105769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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