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Article

Increased susceptibility to diet-induced obesity in GPRC6A receptor knockout mice.

The Journal of endocrinology - 1 May 2013

Clemmensen Christoffer, Smajilovic Sanela, Madsen Andreas N, Klein Anders B, Holst Birgitte, Bräuner-Osborne Hans

Abstract excerpt

The recently identified G protein-coupled receptor GPRC6A is activated by dietary amino acids and expressed in multiple tissues. Although the receptor is hypothesised to exert biological impact on metabolic and endocrine-related parameters, the role of the receptor in obesity and metabolic complications is still elusive. In the present study, we investigated the impact of GPRC6A deficiency in a murine model of...

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Source

Identifiers

PMID: 23428581
DOI: 10.1530/JOE-12-0550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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