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Article

A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock.

Current biology : CB - 23 Jan 2023

Giesecke Astrid, Johnstone Peter S, Lamaze Angelique, Landskron Johannes, Atay Ezgi, Chen Ko-Fan, Wolf Eva, Top Deniz, Stanewsky Ralf

Abstract excerpt

Circadian clocks are self-sustained molecular oscillators controlling daily changes of behavioral activity and physiology. For functional reliability and precision, the frequency of these molecular oscillations must be stable at different environmental temperatures, known as "temperature compensation." Despite being an intrinsic property of all circadian clocks, this phenomenon is not well understood at the...

Topics

Animals
Drosophila
Circadian Clocks
Drosophila melanogaster
Temperature
Drosophila Proteins
Circadian Rhythm
Active Transport, Cell Nucleus
Reproducibility of Results
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

CLOCK Proteins

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Identifiers

PMID: 36584676
DOI: 10.1016/j.cub.2022.12.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-36584676-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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