Article
The timSL mutant of the Drosophila rhythm gene timeless manifests allele-specific interactions with period gene mutants.
Neuron - 1 Nov 1996
Rutila J E, Zeng H, Le M, Curtin K D, Hall J C, Rosbash M
Abstract excerpt
To identify new components of the Drosophila circadian clock, we screened chemically mutagenized flies for suppressors or enhancers of the long periods characteristic of the period (per) mutant allele perL. We isolated a novel mutant that maps to the rhythm gene timeless (tim). This novel allele, timSL, alters the temporal pattern of perL protein nuclear localization and restores temperature compensation to perL...
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