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Article

The CoREST complex regulates multiple histone modifications temporal-specifically in clock neurons.

Open biology - 1 Jul 2024

Lv Pengfei, Zhao Zhangwu, Hirano Yukinori, Du Juan

Abstract excerpt

Epigenetic regulation is important for circadian rhythm. In previous studies, multiple histone modifications were found at the Period (Per) locus. However, most of these studies were not conducted in clock neurons. In our screen, we found that a CoREST mutation resulted in defects in circadian rhythm by affecting Per transcription. Based on previous studies, we hypothesized that CoREST regulates circadian rhythm...

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Identifiers

PMID: 38981515
DOI: 10.1098/rsob.230355
PMCID: PMC11285899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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