Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-Cell RNA Sequencing Reveals Heterogeneity in the Tumor Microenvironment between Young-Onset and Old-Onset Colorectal Cancer

12 Dec 2022

Abstract excerpt

BACKGROUND: The incidence of sporadic young-onset colorectal cancer (yCRC) is increasing. Compared with old-onset colorectal cancer (oCRC), yCRC has different clinical and molecular characteristics. However, the difference in the tumor microenvironment (TME) between yCRC and oCRC remains unclear. METHODS: Fourteen untreated CRC tumor samples were subjected to single-cell RNA sequencing analysis. RESULTS: B cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Ferroptosis and cancer prognosis
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36551288
DOI: 10.3390/biom12121860

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-Cell RNA Sequencing Reveals Heterogeneity in the Tumor Microenvironment between Young-Onset and Old-Onset Colorectal CancerPMID 36551288Read ↗

Single-cell integration analysis reveals molecular signatures of the tumor microenvironment in early-onset colorectal cancerSemantic proximity Read ↗

Single-Cell RNA Sequencing and Inferred Protein Activity Analysis Reveal a Distinct Tumor Phenotype in Early-Onset Colorectal Cancer PatientsSemantic proximity Read ↗

Integrated Single‐Cell RNA ‐Seq Reveals Immunosuppressive Mechanisms of Treg Cell Differentiation and Tumor Microenvironment Interactions in Colorectal CancerSemantic proximity Read ↗

Multiregion single‐cell sequencing reveals the transcriptional landscape of the immune microenvironment of colorectal cancerSemantic proximity Read ↗

Identification of differentially expressed genes and splicing events in early-onset colorectal cancerSemantic proximity Read ↗

Epigenetic Modulation, Intra-tumoral Microbiome and Immunity in Early Onset Colorectal CancerSemantic proximity Read ↗

Molecular genetics of early-onset colorectal cancerSemantic proximity Read ↗

Single-Cell Transcriptome Analysis Reveals Heterogeneity and Convergence of the Tumor Microenvironment in CRCSemantic proximity Read ↗

Single-cell transcriptome analysis reveals heterogeneity and convergence of the tumor microenvironment in colorectal cancerSemantic proximity Read ↗

Single-Cell Transcriptomic Profiling Reveals T-Cell Functional Shifts in Primary Versus Metastatic Colorectal CancerSemantic proximity Read ↗

Distinct intratumoral microbiome of young-onset and average-onset colorectal cancerSemantic proximity Read ↗

Single‐cell analyses reveal suppressive tumor microenvironment of human colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.