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Multiregion single‐cell sequencing reveals the transcriptional landscape of the immune microenvironment of colorectal cancer

1 Jan 2021

Abstract excerpt

Abstract The tumor microenvironment is a complex ecosystem formed by distinct and interacting cell populations, and its composition is related to cancer prognosis and response to clinical treatment. In this study, we have taken the advantage of two single‐cell RNA sequencing technologies (Smart‐seq2 and DNBelab C4) to generate an atlas of 15,115 immune and nonimmune cells from primary tumors and hepatic...

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PMID: 33463049
DOI: 10.1002/ctm2.253

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