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Single-cell transcriptome analysis reveals heterogeneity and convergence of the tumor microenvironment in colorectal cancer

4 Jan 2023

Abstract excerpt

Introduction: Colorectal cancer (CRC) ranks second for mortality and third for morbidity among the most commonly diagnosed cancers worldwide. We aimed to investigate the heterogeneity and convergence of tumor microenvironment (TME) in CRC. Methods: We analyzed the single-cell RNA sequencing data obtained from the Gene Expression Omnibus (GEO) database and identified 8 major cell types and 25 subgroups derived...

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PMID: 36685571
DOI: 10.3389/fimmu.2022.1003419

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