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Article

The genomic landscape of low-grade serous ovarian/peritoneal carcinoma and its impact on clinical outcomes.

Gynecologic oncology - 1 Jun 2022

Gershenson David M, Sun Charlotte C, Westin Shannon N, Eyada Mostafa, Cobb Lauren P, Nathan Lisa C, Sood Anil K, Malpica Anais, Hillman Robert T, Wong Kwong K

Abstract excerpt

OBJECTIVE: Low-grade serous carcinoma (LGSOC) is a rare epithelial ovarian/peritoneal cancer characterized by younger age at diagnosis, relative chemoresistance, prolonged overall survival (OS), and mutations in the mitogen activated protein kinase (MAPK) pathway compared to high-grade serous carcinoma. We describe the genomic profile of LGSOC by next generation sequencing (NGS) and evaluated its potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35606067
DOI: 10.1016/j.ygyno.2021.11.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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