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Article

Dietary Sugar Shifts Mitochondrial Metabolism and Small RNA Biogenesis in Sperm

12 Dec 2022

Abstract excerpt

Aims: Increasing concentrations of dietary sugar results in a linear accumulation of triglycerides in male Drosophila, while inducing a U-shaped obesity response in their offspring. Here, using a combination of proteomics and small RNA (sRNA) sequencing, we aimed at understanding the molecular underpinning in sperm for such plasticity. Results: Proteomic analysis of seminal vesicles revealed that increasing...

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PMID: 36509450
DOI: 10.1089/ars.2022.0049

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