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Article

Small Noncoding RNAs Contribute to Sperm Oxidative Stress-Induced Programming of Behavioral and Metabolic Phenotypes in Offspring.

Oxidative medicine and cellular longevity - 1 Jan 2022

Ren Li, Xin Yining, Sun Xiaoxiao, Zhang Yanwen, Chen Yingqi, Liu Suyuan, He Bin

Abstract excerpt

There is growing evidence that paternal environmental information alters small noncoding RNAs (sncRNAs) in sperm and in turn can induce alterations of metabolic and behavioral phenotypes of the next generation. However, the potential mediators of the effects remain to be elucidated. A great diversity of environmental insults and stresses can convergently induce the elevation of reactive oxygen species (ROS) in...

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Identifiers

PMID: 35707281
DOI: 10.1155/2022/6877283
PMCID: PMC9192199

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