Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs

5 Jun 2024

Abstract excerpt

Abstract Spermatozoa harbour a complex and environment-sensitive pool of small non-coding RNAs (sncRNAs)1, which influences offspring development and adult phenotypes1–7. Whether spermatozoa in the epididymis are directly susceptible to environmental cues is not fully understood8. Here we used two distinct paradigms of preconception acute high-fat diet to dissect epididymal versus testicular contributions to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38839949
DOI: 10.1038/s41586-024-07472-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAsPMID 38839949Read ↗

Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic InformationSemantic proximity Read ↗

Alterations in sperm RNAs persist after alcohol cessation and correlate with epididymal mitochondrial dysfunctionSemantic proximity Read ↗

Role of small RNAs harbored by sperm in embryonic development and offspring phenotype.Semantic proximity Read ↗

Paternal Obesity, Interventions, and Mechanistic Pathways to Impaired Health in OffspringSemantic proximity Read ↗

High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspringSemantic proximity Read ↗

Sperm microRNA Content Is Altered in a Mouse Model of Male Obesity, but the Same Suite of microRNAs Are Not Altered in Offspring’s SpermSemantic proximity Read ↗

Heavy Chronic Intermittent Ethanol Exposure Alters Small Noncoding RNAs in Mouse Sperm and EpididymosomesSemantic proximity Read ↗

How do lifestyle and environmental factors influence the sperm epigenome? Effects on sperm fertilising ability, embryo development, and offspring healthSemantic proximity Read ↗

Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs.Semantic proximity Read ↗

Epididymal RNase T2 contributes to astheno-teratozoospermia and intergenerational metabolic disorder through epididymosome-sperm interactionSemantic proximity Read ↗

Male Obesity: Epigenetic Origin and Effects in Sperm and OffspringSemantic proximity Read ↗

Small RNAs are trafficked from the epididymis to developing mammalian spermSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.