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Sex Differences in Intestinal Carbohydrate Metabolism Promote Food Intake and Sperm Maturation

1 Aug 2019

Abstract excerpt

Physiology and metabolism are often sexually dimorphic, but the underlying mechanisms remain incompletely understood. Here, we use the intestine of Drosophila melanogaster to investigate how gut-derived signals contribute to sex differences in whole-body physiology. We find that carbohydrate handling is male-biased in a specific portion of the intestine. In contrast to known sexual dimorphisms in invertebrates,...

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PMID: 31398343
DOI: 10.1016/j.cell.2019.07.029

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