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Article

Inferring selection effects in SARS-CoV-2 with Bayesian Viral Allele Selection.

PLoS genetics - 1 Dec 2022

Jankowiak Martin, Obermeyer Fritz H, Lemieux Jacob E

Abstract excerpt

The global effort to sequence millions of SARS-CoV-2 genomes has provided an unprecedented view of viral evolution. Characterizing how selection acts on SARS-CoV-2 is critical to developing effective, long-lasting vaccines and other treatments, but the scale and complexity of genomic surveillance data make rigorous analysis challenging. To meet this challenge, we develop Bayesian Viral Allele Selection (BVAS), a...

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PMID: 36508459
DOI: 10.1371/journal.pgen.1010540
PMCID: PMC9779722

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