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Article

Natural selection driven by escape from shifting antibody classes shapes SARS-CoV-2 evolution

2026-03-20

Abstract excerpt

The phenotypic fitness landscape defines the action of natural selection on pathogens, linking changes in their phenotypes to transmission and evolution. The rapidly changing nature of epidemic spread and antigenic landscapes pushes viruses to evolve on fitness seascapes. As a result, evolution of viruses such as SARS-CoV-2 proceeds in a never ending series of waves, driven by epistatic interactions and by the arm...

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Identifiers and source

Literature Corpus work
c87c328e-3fe3-5fcb-9bfe-506b70b2592e
DOI
10.64898/2026.03.19.712895
Open publication

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Natural selection driven by escape from shifting antibody classes shapes SARS-CoV-2 evolutionDOI 10.64898/2026.03.19.712895
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