Article
Evaluating the effect of SARS-CoV-2 spike mutations with a linear doubly robust learner.
Frontiers in cellular and infection microbiology - 1 Jan 2023
Wang Xin, Hu Mingda, Liu Bo, Xu Huifang, Jin Yuan, Wang Boqian, Zhao Yunxiang, Wu Jun, Yue Junjie, Ren Hongguang
Abstract excerpt
Driven by various mutations on the viral Spike protein, diverse variants of SARS-CoV-2 have emerged and prevailed repeatedly, significantly prolonging the pandemic. This phenomenon necessitates the identification of key Spike mutations for fitness enhancement. To address the need, this manuscript formulates a well-defined framework of causal inference methods for evaluating and identifying key Spike mutations to...
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