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Article

Inferring effects of mutations on SARS-CoV-2 transmission from genomic surveillance data.

Nature communications - 7 Jan 2025

Lee Brian, Quadeer Ahmed Abdul, Sohail Muhammad Saqib, Finney Elizabeth, Ahmed Syed Faraz, McKay Matthew R, Barton John P

Abstract excerpt

New and more transmissible variants of SARS-CoV-2 have arisen multiple times over the course of the pandemic. Rapidly identifying mutations that affect transmission could improve our understanding of viral biology and highlight new variants that warrant further study. Here we develop a generic, analytical epidemiological model to infer the transmission effects of mutations from genomic surveillance data. Applying...

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Identifiers

PMID: 39774959
DOI: 10.1038/s41467-024-55593-0

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