Article

Predicting the mutational drivers of future SARS-CoV-2 variants of concern

2021-06-22

Abstract excerpt

SARS-CoV-2 evolution threatens vaccine- and natural infection-derived immunity, and the efficacy of therapeutic antibodies. Herein we sought to predict Spike amino acid changes that could contribute to future variants of concern. We tested the importance of features comprising epidemiology, evolution, immunology, and neural network-based protein sequence modeling. This resulted in identification of the primary bio...

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Literature Corpus work: 3a057bd1-3526-5bd0-86c0-16f2b49d7023
DOI: 10.34944/dspace/6982

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