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Article

Disease patterns of coronary heart disease and type 2 diabetes harbored distinct and shared genetic architecture.

Cardiovascular diabetology - 9 Dec 2022

Xiao Han, Ma Yujia, Zhou Zechen, Li Xiaoyi, Ding Kexin, Wu Yiqun, Wu Tao, Chen Dafang

Abstract excerpt

BACKGROUND: Coronary heart disease (CHD) and type 2 diabetes (T2D) are two complex diseases with complex interrelationships. However, the genetic architecture of the two diseases is often studied independently by the individual single-nucleotide polymorphism (SNP) approach. Here, we presented a genotypic-phenotypic framework for deciphering the genetic architecture underlying the disease patterns of CHD and T2D....

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Share to Coronary Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 36494812
DOI: 10.1186/s12933-022-01715-1
PMCID: PMC9738029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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