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Exploring the Genetic Relationship Between Type 2 Diabetes and Cardiovascular Disease: A Large-Scale Genetic Association and Polygenic Risk Score Study.

Biomolecules - 18 Nov 2024

Yao Ziwei, Zhang Xiaomai, Deng Liufei, Zhang Jiayu, Wen Yalu, Zheng Deqiang, Liu Long

Abstract excerpt

Type 2 diabetes (T2D) is often comorbid with cardiovascular diseases (CVDs). The direction of causation between T2D and CVD is difficult to determine; however, there may be a common underlying pathway attributable to shared genetic factors. We aimed to determine whether there is a shared genetic susceptibility to T2D and CVD. This study utilizes large-scale datasets from the UK Biobank (UKB) and DIAGRAM...

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Share to Cardiovascular Diseases
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Risk Score

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Multifactorial Inheritance

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

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Identifiers

PMID: 39595643
DOI: 10.3390/biom14111467
PMCID: PMC11592259

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