Article
Association between ten-eleven methylcytosine dioxygenase 2 genetic variation and viral load in people with HIV.
AIDS (London, England) - 1 Mar 2023
Murray Daniel D, Grund Birgit, MacPherson Cameron R, Ekenberg Christina, Zucco Adrian G, Reekie Joanne, Dominguez-Dominguez Lourdes, Leung Preston, Fusco Dahlene, Gras Julien, Gerstoft Jan, Helleberg Marie, Borges Álvaro H, Polizzotto Mark N, Lundgren Jens D
Abstract excerpt
INTRODUCTION: Identifying genetic factors that influence HIV-pathogenesis is critical for understanding disease pathways. Previous studies have suggested a role for the human gene ten-eleven methylcytosine dioxygenase 2 (TET2) in modulating HIV-pathogenesis. METHODS: We assessed whether genetic variation in TET2 was associated with markers of HIV-pathogenesis using both gene level and single nucleotide...
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