Article
Bone marrow stromal antigen 2 (BST-2) genetic variants influence expression levels and disease outcome in HIV-1 chronically infected patients
2021-08-23
Abstract excerpt
<title>Abstract</title> <p>BackgroundBone marrow stromal antigen 2 (BST-2) also known as Tetherin (CD317/HM1.24), is a host restriction factor that blocks the release of HIV-1 virions from infected cells. Previous studies reported that BST-2 genetic variants or single nucleotide polymorphims (SNPs) have a preventative role during HIV-1 infection. However, the influence of BST-2 SNPs on expression levels remains u...
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Identifiers and source
- Literature Corpus work
- 54e02545-ceef-5347-be1e-dd6a615db13d
- DOI
- 10.21203/rs.3.rs-820725/v1
