Article
Human genetic variation in HIV disease: beyond genome-wide association studies.
Current opinion in HIV and AIDS - 1 Mar 2015
McLaren Paul J, Fellay Jacques
Abstract excerpt
PURPOSE OF REVIEW: Rapid expansion of genomic technologies has resulted in an unprecedented ability to interrogate the impact of human genetic variation on disease. HIV-1 infection is a unique model for studying this impact because host genetic variation influences both clinical outcome and the genetic sequence and evolution of the pathogen itself. RECENT FINDINGS: Several candidate gene studies have proposed...
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