Article
CD4 intragenic SNPs associate with HIV-2 plasma viral load and CD4 count in a community-based study from Guinea-Bissau, West Africa.
Journal of acquired immune deficiency syndromes (1999) - 1 Jan 2011
Hennig Branwen J, Velez-Edwards Digna R, Schim van der Loeff Maarten F, Bisseye Cyrille, Edwards Todd L, Tacconelli Alessandra, Novelli Giuseppe, Aaby Peter, Kaye Steve, Scott William K, Jaye Assan, Whittle Hilton C, Williams Scott M, Hill Adrian V, Sirugo Giorgio
Abstract excerpt
OBJECTIVES: The human genetics of HIV-2 infection and disease progression is understudied. Therefore, we studied the effect of variation in 2 genes that encode products critical to HIV pathogenesis and disease progression: CD4 and CD209. DESIGN: This cross-sectional study consisted of 143 HIV-2, 30 HIV-1 + HIV-2 and 29 HIV-1-infected subjects and 194 uninfected controls recruited from rural Guinea-Bissau....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.