Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BACE2: A Promising Neuroprotective Candidate for Alzheimer’s Disease

26 Nov 2022

Abstract excerpt

Alzheimer's disease (AD) is the most common cause of dementia that affects millions of predominantly elderly individuals worldwide. Despite intensive research over several decades, controversies still surround the etiology of AD and the disease remains incurable. Meanwhile, new molecular players of the central amyloid cascade hypothesis have emerged and among these is a protease known as β-site APP cleavage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Cholinesterase and Neurodegenerative Diseases
Share to Computational Drug Discovery Methods

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36463454
DOI: 10.3233/jad-220867

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BACE2: A Promising Neuroprotective Candidate for Alzheimer’s DiseasePMID 36463454Read ↗

Physiological Functions of the β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2Semantic proximity Read ↗

The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology.Semantic proximity Read ↗

A Review of the Familial Alzheimer’s Disease Locus PRESENILIN 2 and Its Relationship to PRESENILIN 1Semantic proximity Read ↗

Generation of an Alzheimer’s Disease Model Derived from Induced Pluripotent Stem Cells with an APP Gene MutationSemantic proximity Read ↗

Alzheimer's Disease: Mechanism and Approach to Cell Therapy.Semantic proximity Read ↗

BACE1 (β-secretase) inhibitors for the treatment of Alzheimer's diseaseSemantic proximity Read ↗

Distinct transcriptional regulation and function of the human BACE2 and BACE1 genesSemantic proximity Read ↗

Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer’s Disease and CSF Amyloid Biomarkers in APOE ε4 Non-CarriersSemantic proximity Read ↗

Identification of Human Islet Amyloid Polypeptide as a BACE2 Substrate.Semantic proximity Read ↗

Natural compounds that modulate BACE1-processing of amyloid-beta precursor protein in Alzheimer's disease.Semantic proximity Read ↗

BACE1 Structure and Function in Health and Alzheimers DiseaseSemantic proximity Read ↗

Modeling familial Alzheimer's disease with induced pluripotent stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.