Article
Genetic screening and analysis of TUBB8 variants in females seeking ART.
Reproductive biomedicine online - 1 Feb 2023
Lin Tingting, Liu Weiwei, Han Wei, Tong Keya, Xiang Yezhou, Liao Haiyuan, Chen Ke, He Yao, Liu Dongyun, Huang Guoning
Abstract excerpt
RESEARCH QUESTION: More than 100 variants have been identified in the TUBB8 gene, which account for approximately 30% of infertile women with oocyte maturation defects. But what is the correlation between the highly phenotypic diversity and genetic variability? Are there other variants in TUBB8 related to female infertility? DESIGN: TUBB8 resequencing was performed in 80 female subjects who were experiencing...
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