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Article

The comprehensive variant and phenotypic spectrum of TUBB8 in female infertility.

Journal of assisted reproduction and genetics - 1 Sept 2021

Zheng Wei, Hu Huiling, Zhang Shuoping, Xu Xilin, Gao Yong, Gong Fei, Lu Guangxiu, Lin Ge

Abstract excerpt

PURPOSE: TUBB8 is a gene that is frequently analysed in the genetic diagnosis of female infertility; 102 variants of this gene have been identified. However, the evaluation of its pathogenicity and the resulting phenotypes vary. Here, we aimed to identify novel TUBB8 variants as well as to summarize the reported variants and phenotypes in order for them to be included in genetic counselling analyses. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33970371
DOI: 10.1007/s10815-021-02219-9
PMCID: PMC8490578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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