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Article

Mutation analysis of the TUBB8 gene in nine infertile women with oocyte maturation arrest.

Reproductive biomedicine online - 1 Sept 2017

Huang Lingli, Tong Xianhong, Luo Lihua, Zheng Shengxia, Jin Rentao, Fu Yingyun, Zhou Guixiang, Li Daojing, Liu Yusheng

Abstract excerpt

Mutations in the tubulin beta 8 class VIII (TUBB8) gene have been proven to cause oocyte maturation arrest. The aim of this study was to describe newly discovered mutations in TUBB8 and to investigate the prevalence of TUBB8 mutations in our cohort. Nine women with oocyte maturation arrest and 100 fertile female controls were recruited. Sanger sequencing of the coding regions of TUBB8 revealed a heterozygous...

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Source

Identifiers

PMID: 28652098
DOI: 10.1016/j.rbmo.2017.05.017

Genes

TUBB8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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