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Article

Novel variants in TUBB8 gene cause multiple phenotypic abnormalities in human oocytes and early embryos.

Journal of ovarian research - 25 Nov 2023

Hu Tingwenyi, Li Chong, Qiao Sen, Liu Weiwei, Han Wei, Li Wei, Shi Rong, Xue Xia, Shi Juanzi, Huang Guoning, Lin Tingting

Abstract excerpt

BACKGROUND: The genotype-phenotype relationships between TUBB8 variants and female infertility are difficult to clearly define due to the complex inheritance patterns and the highly heterogeneous phenotypes. This study aims to identify novel TUBB8 variants and relevant phenotypes in more infertile females. METHODS: A total of 35 females with primary infertility were recruited from two reproductive centers and...

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Identifiers

PMID: 38007525
DOI: 10.1186/s13048-023-01274-3
PMCID: PMC10675859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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