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Article

SNPs in 3'UTR miRNA Target Sequences Associated with Individual Drug Susceptibility.

International journal of molecular sciences - 8 Nov 2022

Rykova Elena, Ershov Nikita, Damarov Igor, Merkulova Tatiana

Abstract excerpt

The complementary interaction of microRNAs (miRNAs) with their binding sites in the 3'untranslated regions (3'UTRs) of target gene mRNAs represses translation, playing a leading role in gene expression control. MiRNA recognition elements (MREs) in the 3'UTRs of genes often contain single nucleotide polymorphisms (SNPs), which can change the binding affinity for target miRNAs leading to dysregulated gene...

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Identifiers

PMID: 36430200
DOI: 10.3390/ijms232213725
PMCID: PMC9692299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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