Article
MicroRNA pharmacogenomics: post-transcriptional regulation of drug response.
Trends in molecular medicine - 1 Aug 2011
Rukov Jakob Lewin, Shomron Noam
Abstract excerpt
The field of pharmacogenomics aims to predict which drugs will be most effective and safe for a particular individual based on their genome sequence or expression profile, thereby allowing personalized treatment. The bulk of pharmacogenomic research has focused on the role of single nucleotide polymorphisms, copy number variations or differences in gene expression levels of drug metabolizing or transporting genes...
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