Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA methylation and personalized medicine.

Journal of clinical pharmacy and therapeutics - 1 Dec 2014

Tang J, Xiong Y, Zhou H-H, Chen X-P

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: Variation in the expression of drug-response-related genes contributes significantly to interindividual differences in drug response. DNA methylation is one of the most common epigenetic modifications that control gene expression. DNA methylation may occur in genes encoding drug metabolizing enzymes (DMEs), drug transporters and drug targets, and can thereby alter the pharmacokinetics...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Methylation
Share to Drug Resistance
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Transport Proteins

Share to MicroRNAs

Share to Pharmacogenetics

Share to Precision Medicine

Share to Biological Transport

Source

Identifiers

PMID: 25230364
DOI: 10.1111/jcpt.12206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA methylation and personalized medicine.PMID 25230364Read ↗

Epigenetic Regulation of Genes Encoding Drug-Metabolizing Enzymes and Transporters; DNA Methylation and Other MechanismsSemantic proximity Read ↗

Epigenetic techniques in pharmacogenetics.Semantic proximity Read ↗

DNA Methylation of ADME GenesSemantic proximity Read ↗

Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicitySemantic proximity Read ↗

Epigenetic regulation of drug transporter expression in human tissuesSemantic proximity Read ↗

Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymesSemantic proximity Read ↗

Epigenetic Changes in Gene Expression for Drug‐Metabolizing Enzymes and TransportersSemantic proximity Read ↗

Impact of Individual Factors on DNA Methylation of ADME Genes: A Systematic ReviewSemantic proximity Read ↗

Epigenetic alternations and cancer chemotherapy response.Semantic proximity Read ↗

Pharmacogenetics of Drugs Used in the Treatment of CancersSemantic proximity Read ↗

ATP-binding cassette transmembrane transporters and their epigenetic control in cancer: an overviewSemantic proximity Read ↗

Epigenetics and OncologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.