Article
Clinical applicability of sequence variations in genes related to drug metabolism.
Current drug metabolism - 1 Jun 2011
Stojiljkovic Maja, Patrinos George P, Pavlovic Sonja
Abstract excerpt
The Human Genome and the Hap Map Projects as well as the extensive use of deep resequencing worldwide, have contributed to a massive catalogue of reported single nucleotide polymorphisms (SNPs) and other genetic variations in the human genome. Pharmacogenomics is an emerging field that combines genetics with pharmacokinetics and pharmacodynamics of the drug in attempt to understand inter-individual differences...
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