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Article

Transcriptional regulation and pharmacogenomics.

Pharmacogenomics - 1 May 2011

Georgitsi Marianthi, Zukic Branka, Pavlovic Sonja, Patrinos George P

Abstract excerpt

Interindividual variable drug response is correlated with sequence alterations in genes encoding drug-metabolizing enzymes and transporters, affecting drug absorption, distribution, metabolism and excretion. This variable drug response may have an impact on disease therapeutic outcomes, tolerance to adverse drug reactions and even survival. Sequence alterations may occur not only within the coding region of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21619428
DOI: 10.2217/pgs.10.215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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