Article
The relationship between lipoprotein(a) and risk of cardiovascular disease: a Mendelian randomization analysis.
European journal of medical research - 27 Oct 2022
Wang Shiyue, Zha Li, Chen Jian, Du Dongjie, Liu Danyang, Zhong Ming, Shang Rongfang, Sun Dongxue, Sun Chang, Jin Enze
Abstract excerpt
BACKGROUND: Lipoprotein(a) [Lp(a)] is one of the residual risk factors for cardiovascular disease (CVD) in the setting of optimal low-density lipoprotein cholesterol (LDL-C). The association between Lp(a) and CVD is still in the exploratory phase, with few studies indicating a causal connection between Lp(a) and various CVD. METHODS: Lp(a) (n = 377,590) was a genome-wide association study (GWAS) based on European...
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