Article
Association of Lipoprotein (a) variants with risk of cardiovascular disease: a Mendelian randomization study.
Lipids in health and disease - 1 Jun 2021
Xia Juan, Guo Chunyue, Liu Kuo, Xie Yunyi, Cao Han, Peng Wenjuan, Sun Yanyan, Liu Xiaohui, Li Bingxiao, Zhang Ling
Abstract excerpt
BACKGROUND: There is a well-documented empirical relationship between lipoprotein (a) [Lp(a)] and cardiovascular disease (CVD); however, causal evidence, especially from the Chinese population, is lacking. Therefore, this study aims to estimate the causal association between variants in genes affecting Lp(a) concentrations and CVD in people of Han Chinese ethnicity. METHODS: Two-sample Mendelian randomization...
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