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Article

Lipoprotein(a) and stroke: a two-sample Mendelian randomization study

12 May 2023

Abstract excerpt

Background To evaluate the causal relationship between lipoprotein(a) Lp(a) and stroke risk. Method Adopting two grand scale genome-wide association study (GWAS) databases, the instrumental variables were selected on the basis that the genetic loci met the criteria of being independent of each other and closely related to Lp(a). Summary-level data for outcomes, ischemic stroke and its subtypes were acquired from...

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Identifiers

PMID: 37251802
DOI: 10.3389/fnagi.2023.1178079

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