Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Elevated Lipoprotein(a) and Risk of Atrial Fibrillation: An Observational and Mendelian Randomization Study.

Journal of the American College of Cardiology - 26 Apr 2022

Mohammadi-Shemirani Pedrum, Chong Michael, Narula Sukrit, Perrot Nicolas, Conen David, Roberts Jason D, Thériault Sébastien, Bossé Yohan, Lanktree Matthew B, Pigeyre Marie, Paré Guillaume

Abstract excerpt

BACKGROUND: Atrial fibrillation (AF) is a cardiac arrhythmia associated with an elevated risk of stroke, heart failure, and mortality. However, preventative therapies are needed with ancillary benefits on its cardiovascular comorbidities. Lipoprotein(a) (Lp[a]) is a recognized risk factor for atherosclerotic cardiovascular disease (ASCVD), which itself increases AF risk, but it remains unknown whether Lp(a) is a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrial Fibrillation
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoprotein(a)

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 35450575
DOI: 10.1016/j.jacc.2022.02.018
PMCID: PMC9584800

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Elevated Lipoprotein(a) and Risk of Atrial Fibrillation: An Observational and Mendelian Randomization Study.PMID 35450575Read ↗

Causal effects of plasma lipids on the risk of atrial fibrillation: A multivariable mendelian randomization study.Semantic proximity Read ↗

The Relationship between Blood Lipids and Risk of Atrial Fibrillation: Univariable and Multivariable Mendelian Randomization Analysis.Semantic proximity Read ↗

Associations of lipids and lipid-modifying drug target genes with atrial fibrillation risk based on genomic data.Semantic proximity Read ↗

Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry.Semantic proximity Read ↗

The relationship between lipoprotein(a) and risk of cardiovascular disease: a Mendelian randomization analysis.Semantic proximity Read ↗

Factorial Mendelian randomization of lipoprotein (a) lowering, low-density lipoprotein cholesterol lowering, and lifestyle improvements: joint associations with cardiovascular risk.Semantic proximity Read ↗

Genetic susceptibility, elevated blood pressure, and risk of atrial fibrillation: a Mendelian randomization study.Semantic proximity Read ↗

Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes: Mendelian Randomization and Observational Analyses.Semantic proximity Read ↗

Evaluating genetically-predicted causal effects of lipoprotein(a) in human diseases: a phenome-wide Mendelian randomization studySemantic proximity Read ↗

Acquired risk factors and incident atrial fibrillation according to age and genetic predisposition.Semantic proximity Read ↗

Blood lipid profiles and risk of atrial fibrillation: A systematic review and meta-analysis of cohort studies.Semantic proximity Read ↗

Lipoprotein(a): An independent, genetic, and causal factor for cardiovascular disease and acute myocardial infarctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.