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Article

Annotating genetic variants to target genes using H-MAGMA.

Nature protocols - 1 Jan 2023

Sey Nancy Y A, Pratt Brandon M, Won Hyejung

Abstract excerpt

An outstanding goal in modern genomics is to systematically predict the functional outcome of noncoding variation associated with complex traits. To address this, we developed Hi-C-coupled multi-marker analysis of genomic annotation (H-MAGMA), which builds on traditional MAGMA-a gene-based analysis tool that assigns variants to their target genes-by incorporating 3D chromatin configuration in assigning variants...

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Identifiers

PMID: 36289406
DOI: 10.1038/s41596-022-00745-z
PMCID: PMC10026181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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