Article
Endoplasmic reticulum aminopeptidases in the pathogenesis of ankylosing spondylitis: Fig. 1
11 Jun 2015
Abstract excerpt
There has been significant progress in our understanding of the pathogenesis of AS. The advent of genome-wide association studies has increased the known loci associated with AS to more than 40. The endoplasmic reticulum resident aminopeptidases (ERAP) 1 and 2 were identified in this manner and are of particular interest. There appears to be a genetic as well as a functional interaction of ERAP1 and 2 with...
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