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Article

Age at Menarche Mediating Visceral Adipose Tissue's Influence on Pre-eclampsia: A Mendelian Randomization Study.

The Journal of clinical endocrinology and metabolism - 17 Jan 2023

Deng Peizhi, Yu Qingwei, Tang Haibo, Lu Yao, He Yingdong

Abstract excerpt

CONTEXT: The association between visceral adipose tissue (VAT) and pre-eclampsia (PE) shows inconsistent results and the underlying mediator remains unknown. OBJECTIVE: We aimed to explore the causal effect of VAT on PE risks and the mediation role of age at menarche (AAM) in explaining this relationship. METHODS: Summary data for PE were obtained from the FinnGen genome-wide association study (3556 cases and 114...

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Source

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Identifiers

PMID: 36184738
DOI: 10.1210/clinem/dgac566
PMCID: PMC9844965

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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