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Article

Age at menarche and ischemic heart disease: An update mendelian randomization study

3 Nov 2022

Abstract excerpt

Background: Although earlier menarche age has been associated with ischemic heart disease in previous observational studies, the relationship’s causation has not been shown. Through two-sample Mendelian randomization (MR), we were able to define the causal connection. Methods: We performed Mendelian Randomization (MR) analysis to explore the associations between genetically predicted AAM and IHD. Summary-level...

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PMID: 36406117
DOI: 10.3389/fgene.2022.942861

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