Article
Bidirectional Mendelian Randomization Analysis of Genetic Proxies of Plasma Fatty Acids and Pre-Eclampsia Risk.
Nutrients - 31 Oct 2024
Zhou Jingqi, Jiang Shuo, Liu Dangyun, Li Xinyi, Zhou Ziyi, Wang Zhiheng, Wang Hui
Abstract excerpt
BACKGROUND: Previous studies have reported associations between fatty acids and the risk of pre-eclampsia. However, the causality of these associations remains uncertain. This study postulates a causal relationship between specific plasma fatty acids and pre-eclampsia or other maternal hypertensive disorders (PE-HTPs). To test this hypothesis, two-sample bidirectional Mendelian randomization (MR) analyses were...
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