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Article

Causal relationships between birth weight, childhood obesity and age at menarche: A two-sample Mendelian randomization analysis.

Clinical endocrinology - 1 Feb 2023

Wang Lianke, Xu Fei, Zhang Qiang, Chen Jiajun, Zhou Qianyu, Sun Changqing

Abstract excerpt

OBJECTIVES: Observational studies suggest birth weight and childhood obesity are closely associated with age at menarche. However, the relationships between them are currently inconsistent and it remains elusive whether such associations are causal. Therefore, the aim of the study was to investigate whether there existed causal relationships between birth weight, childhood obesity and age at menarche. DESIGN,...

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PMID: 36237121
DOI: 10.1111/cen.14831

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