Article
Causal pathways in preeclampsia: a Mendelian randomization study in European populations.
Frontiers in endocrinology - 1 Jan 2024
Tan Zilong, Ding Mengdi, Shen Jianwu, Huang Yuxiao, Li Junru, Sun Aochuan, Hong Jing, Yang Yan, He Sheng, Pei Chao, Luo Ran
Abstract excerpt
Purpose: Our study utilizes Mendelian Randomization (MR) to explore the causal relationships between a range of risk factors and preeclampsia, a major contributor to maternal and perinatal morbidity and mortality. Methods: Employing the Inverse Variance Weighting (IVW) approach, we conducted a comprehensive multi-exposure MR study analyzing genetic variants linked to 25 risk factors including metabolic disorders,...
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